Smile House opens in Tribeca with a new take on dental wellness

Smile House, now open at 55 Warren Street in Tribeca, reimagines the dental experience by treating the mouth as a gateway to overall health. Founded by Dr. Jonathan B. Levine, the two-story practice combines traditional dentistry with longevity-focused diagnostics, an in-house lab, and a team of multidisciplinary specialists under one roof.

Beyond the typical dental office

Nearly half of adults over 30 have periodontal disease — a condition tied to inflammation, heart disease, diabetes, and accelerated aging. Smile House addresses that connection with care that goes beyond basic cleanings and fillings, integrating oral and systemic health into every patient plan.

What makes it different

The practice uses Mouth Mapping, a diagnostic approach that merges 3D imaging, AI-enhanced scans, and salivary testing to create a full picture of oral health across aesthetics, structure, function, and biology. Think of it as receiving a detailed health report for your mouth and its connection to the rest of your body.

Smile House offers a new approach to dentistry.

Instead of referring patients to multiple offices, Smile House centralizes care — from preventive and cosmetic dentistry to periodontics, orthodontics, oral surgery, pediatric care, sleep medicine, TMJ therapy, and facial aesthetics using EMFACE technology.

Designed to feel l restorative rather than clinical, the space also offers guided breathwork sessions, weighted blankets during procedures, microbiome-friendly snacks, and a 500-square-foot outdoor area.

The backstory

Dr. Levine’s approach stems from his work with the GLO Good Foundation, which he co-founded with his family and Lenny Kravitz in 2011. His experience delivering care in underserved communities shaped his vision for integrating medicine and dentistry to improve long-term health outcomes.

Where to book

Smile House is now open at 55 Warren Street in Tribeca. Visit smilehouse.co for appointment scheduling and service details.