Rerise launches Core100, a 90-day energy protocol with built-in biomarker testing

Most energy products address specific symptoms like the afternoon crash or slow recovery after a hard workout. But fewer are built around the underlying biology that causes these symptoms.

Mitochondria are where your body actually produces energy, and their function erodes with age, stress, and nutrient depletion long before most people think to address it. Rerise wants to build around that gap.

Core100 is Rerise’s debut product, a 90-day protocol designed to support cellular energy production, mental clarity, and recovery. It’s built to work cumulatively, with the first 90 days laying a foundation that builds over time. What sets it apart is the built-in testing layer. Complimentary biomarker draws through Quest Diagnostics are included at no extra cost,  so there’s an objective read on whether biomarkers are actually shifting.

What’s inside Core100

Core100 is built around a stack of evidence-based ingredients, with a few worth calling out specifically:

• NMN supports NAD+ production for steadier energy at the cellular level
• CoQ10 strengthens mitochondrial defenses and supports recovery
• PQQ supports memory and cognitive sharpness
• YuvaBio Y100 is a standardized Terminalia chebula extract that activates autophagy and mitochondrial renewal, and is proprietary to Rerise

The formula also includes supporting nutrients like 5-MTHF, B12, B6, riboflavin, and betaine. To learn more, Rerise breaks down the five core systems Core100 targets right on their website.

What biomarkers get tested

Rerise chose two markers to give users a practical read on two distinct but related systems. hs-CRP tracks systemic inflammation, which drives fatigue, slow recovery, and accelerated aging even when nothing feels obviously wrong. Homocysteine is a strong indicator of cardiovascular and metabolic risk and is directly influenced by the methylation nutrients in Core100’s formula. Taken together, the two markers help create a more practical view of where someone is starting and how that baseline may shift over time. The testing program includes:

• Baseline blood draw at Quest Diagnostics before starting the protocol
• Follow-up draw around day 90
• A “Then vs Now” results comparison from Rerise, with reference ranges and neutral context included
• Ongoing testing every six months for active subscribers

The 90-day guarantee is built around consistency and adherence over the full cycle, not a single lab threshold or biomarker result. For a brand with its sights set on redefining how we approach mitochondrial health and longevity, Core100 may be just the beginning.

Where to order

Available now at rerisehealth.com, US only.