Most healthy smoothies start with a generic marketing claim and work backward to ingredients. Function and Erewhon took the opposite approach.
Their new collaboration, The World’s Healthiest Smoothie?, is built around data from Function’s member base and formulated by Mark Hyman, MD, Function’s co-founder and chief medical officer. The question mark in the name is the point: what’s healthiest depends on your biology, not a label.

The World’s Healthiest Smoothie?
The glass-bottled smoothie is designed to function as a complete meal, with 20 ingredients selected to support metabolic function, blood sugar stability, microbiome health, and inflammation balance.
The smoothie formula leans heavily on blood sugar and cardiovascular support, using ingredients like Ceylon cinnamon, cold-pressed beet juice, and blended omega oils alongside fiber from flaxseed, chia, and green banana. The protein comes from chocho beans, a single-ingredient plant source grown at high altitudes in the Andes, paired with BCAAs and creatine for muscle support. Wild blueberries, pomegranate, and cranberries round out the antioxidant profile, while arugula, fresh herbs, and ginger pack in additional vitamins and minerals.
Function pulled from health data across its member base and found two common gaps: more than 65% of members fall outside the optimal range for fasting insulin, often linked to eating patterns, while 54% show elevated Apolipoprotein B (ApoB), influenced in part by dietary fat quality. The ingredient list was built around those specific markers rather than general wellness claims.
The idea is that the smoothie is an entry point to healthier eating, but understanding your own biology is where lasting health decisions start. Whether the smoothie actually moves the needle on metabolic markers is a longer conversation. Still, the approach of formulating around real data is a meaningful shift in how these products are made—and is far more interesting than a typical celebrity smoothie drop.
Each bottle comes with a QR hang tag offering $25 off a Function membership ($365/year), which includes access to 160+ lab tests and biannual testing covering hormones, thyroid, liver, kidneys, heavy metals, nutrient levels, inflammation markers, and more.
The World’s Healthiest Smoothie? is available now at all Erewhon locations across Southern California through February 2027.