Evvy expands menopause care with new Estradiol Vaginal Cream

Evvy, the vaginal microbiome company known for its precision health platform, has launched a new Estradiol Vaginal Cream, expanding its care suite for peri- and postmenopausal women. The cream is designed to relieve dryness, irritation, and discomfort while supporting both vaginal tissue and microbial balance.

All Evvy prescription (Rx) products are custom compounded.

A precision approach to menopause care

According to data cited by Evvy, up to 84% of women experience vaginal and urinary symptoms during menopause, yet treatment options often address moisture without considering microbial health. Evvy’s formula, compounded in a 503a NABP-accredited pharmacy, works alongside the brand’s Vaginal Health Test and clinical care platform to offer a more complete approach — integrating hormone care with microbiome insights to target the root cause, not just the symptoms.

What sets it apart

Most generic estradiol creams contain parabens, sulfates, or other irritants that can disrupt the vaginal microbiome. Evvy’s compounded formulation avoids unnecessary additives while delivering pure, prescription-grade relief. Users receive guided support through Evvy’s app, which connects testing, treatment, and ongoing clinician feedback.

“Vaginal estrogen is one of the most effective and underused tools for restoring comfort after menopause,” says Dr. Kate McLean, OB-GYN and Chief Medical Officer at Evvy. “Our formula delivers the same effective relief without the unnecessary additives found in most generics.”

Where to buy

Evvy’s Estradiol Vaginal Cream is now available nationwide at evvy.com.